Thermo Fisher Scientific SARS-CoV-2 Spike Protein S1 Polyclonal Antibody
SARS-CoV-2 Spike Protein S1을 인식하는 Rabbit Polyclonal Antibody. WB, IHC, ICC, ELISA에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 항체. 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5 µg/mL |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Anti-SARS-CoV-2 (COVID-19) Spike S1 antibody was raised against a peptide corresponding to 16 amino acids near the amino terminus of SARS-CoV-2 (COVID-19) Spike S1 glycoprotein. The immunogen is located within the first 50 amino acids of SARS-CoV-2 (COVID-19) Spike S1 protein. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2890590 |
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV, is a virus that causes illnesses ranging from mild cold-like symptoms to severe respiratory distress and death. The Spike Protein consists of S1 and S2 domains and serves as the main surface antigen of the coronavirus.
The glycosylated Spike protein, along with the nucleocapsid protein, can be detected in infected cell culture supernatants using antisera from SARS patients. The S1 domain contains a receptor-binding domain (RBD) that specifically binds to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells. Variability in Spike proteins among coronaviruses reflects their diversity in receptor interactions and responses to environmental triggers of virus-cell membrane fusion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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