Thermo Fisher Scientific NR4A3 Monoclonal Antibody (OTI1C1), TrueMAB

Applications

• Western Blot (WB): Tested dilution 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

NOR-1 (NR4A3) is a NR4 nerve growth factor-like receptor involved in neuronal development, T-cell apoptosis, and cancer progression. It binds to NBRE (NGFI-B response element) to regulate the POMC gene. NOR-1 expression is rapidly but transiently induced by various stimuli. Downregulation of NOR-1 and related NGFI-B family members correlates with drug addiction-prone behavior in Lewis rats.
Three human isoforms are known: NOR-1, NOR-1β, and NOR-1 3′ variant.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.