Thermo Fisher Scientific NR4A3 Monoclonal Antibody (OTI1C1), TrueMAB
NR4A3 단백질을 인식하는 Mouse 모노클로날 항체로 Western blot에 적합. Human 시료 반응성. Lyophilized 형태로 제공되며, PBS 및 trehalose 완충액 포함. 재구성 및 결합 실험용으로 적합하며, 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 332–626 of human NR4A3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
NOR-1 (NR4A3) is a NR4 nerve growth factor-like receptor involved in neuronal development, T-cell apoptosis, and cancer progression. It binds to NBRE (NGFI-B response element) to regulate the POMC gene. NOR-1 expression is rapidly but transiently induced by various stimuli. Downregulation of NOR-1 and related NGFI-B family members correlates with drug addiction-prone behavior in Lewis rats.
Three human isoforms are known: NOR-1, NOR-1β, and NOR-1 3′ variant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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