Thermo Fisher Scientific RAD23B Monoclonal Antibody (OTI13A2), TrueMAB
인간 RAD23B 단백질을 인식하는 마우스 단클론 항체. Western blot에 최적화된 TrueMAB 형식. 동결건조된 형태로 제공되며 재구성 후 1 mg/mL 농도 유지. DNA 손상 복구 관련 연구에 적합.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI13A2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–253 of human RAD23B produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The RAD23B gene encodes a human homolog of Saccharomyces cerevisiae Rad23, involved in nucleotide excision repair (NER).
This protein complements the NER defect of xeroderma pigmentosum group C (XP-C) cell extracts and interacts with 3-methyladenine-DNA glycosylase (MPG), suggesting a role in DNA damage recognition during base excision repair.
It contains an N-terminal ubiquitin-like domain that interacts with the 26S proteasome, indicating potential involvement in ubiquitin-mediated proteolysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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