Thermo Fisher Scientific PSCA Polyclonal Antibody
인간 및 랫트에 반응하는 PSCA 폴리클로날 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Protein A로 정제된 고순도 항체이며, KLH 결합 합성 펩타이드(aa 24-123)를 면역원으로 사용했습니다. 암 연구 및 PSCA 발현 분석에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution Range |
|---|---|
| Western Blot (WB) | 1:300–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human PSCA, amino acids 24–123 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
PSCA (Prostate Stem Cell Antigen) is a cell surface antigen that is overexpressed in approximately 40% of primary prostate cancers and up to 100% of metastatic ones. It is also overexpressed in most transitional cell and pancreatic carcinomas. Antibodies against PSCA have been shown to inhibit tumorigenesis, slow tumor growth, prolong survival, and prevent metastasis in preclinical xenograft models, suggesting PSCA may serve as a prognostic marker and/or therapeutic target in prostate cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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