Thermo Fisher Scientific GSTM4 Monoclonal Antibody (4B4)

Applications

Western Blot (WB)

• Tested Dilution: 1–5 µg/mL

ELISA

• Tested Dilution: 10 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
YTDSSYEEKK YTMGDAPDYD RSQWLNEKFK LGLDFPNLPY LIDGAHKITQ SNAILCYIAR KHNLCGETEE EKIRVDILEN QAMDVSNQLA RVCYSPD

Target Information

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. Eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta, and zeta.
This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in detoxification of electrophilic compounds — including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress — by conjugation with glutathione.
Genes encoding the mu class of enzymes are organized in a cluster on chromosome 1p13.3 and are highly polymorphic, which can influence susceptibility to toxins and drug efficacy. Multiple transcript variants encoding distinct protein isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.