Thermo Fisher Scientific GSTM5 Monoclonal Antibody (1G4)

Applications

• ELISA (ELISA)
  Tested Dilution: 10 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
RPWFAGDKIT FVDFLAYDVL DMKRIFEPKC LDAFLNLKDF ISRFEGLKKI SAYMKSSQFL RGLLFGKSAT WNSK

Target Information

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. Eight distinct classes of soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta, and zeta.
This gene encodes a glutathione S-transferase belonging to the mu class. Mu class enzymes detoxify electrophilic compounds such as carcinogens, therapeutic drugs, environmental toxins, and oxidative stress products by conjugation with glutathione.
Genes encoding mu class enzymes are organized in a cluster on chromosome 1p13.3 and are highly polymorphic, affecting susceptibility to carcinogens and drug efficacy. Diversification has occurred in substrate-binding domains and tissue expression patterns to manage various foreign compounds.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.