
Thermo Fisher Scientific SAFB Polyclonal Antibody
SAFB 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, ICC/IF에 사용 가능. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체로, 4°C 단기 및 -20°C 장기 보관 권장. 연구용 전용 제품.
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- PA521356
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment containing a sequence corresponding to a region within amino acids 476–695 (Q15424) of SAFB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11157254 |
Product Specific Information
- Recommended positive controls: A431, H1299, HeLa, HepG2
- Predicted reactivity: Bovine (87%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a DNA-binding protein with high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA).
It is thought to be involved in attaching the base of chromatin loops to the nuclear matrix.
Scaffold attachment factors are a subset of nuclear matrix proteins that bind specifically to S/MAR DNA.
The encoded protein may serve as a molecular base for assembling a transcriptosome complex near actively transcribed genes, regulate heat shock protein 27 transcription, act as an estrogen receptor co-repressor, and is a candidate for breast tumorigenesis.
Multiple transcript variants encoding different isoforms have been identified.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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