Thermo Fisher Scientific SAFB Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Recommended positive controls: A431, H1299, HeLa, HepG2
• Predicted reactivity: Bovine (87%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene encodes a DNA-binding protein with high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA).
It is thought to be involved in attaching the base of chromatin loops to the nuclear matrix.
Scaffold attachment factors are a subset of nuclear matrix proteins that bind specifically to S/MAR DNA.
The encoded protein may serve as a molecular base for assembling a transcriptosome complex near actively transcribed genes, regulate heat shock protein 27 transcription, act as an estrogen receptor co-repressor, and is a candidate for breast tumorigenesis.
Multiple transcript variants encoding different isoforms have been identified.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.