Thermo Fisher Scientific SDHB Monoclonal Antibody (CL0346)
Thermo Fisher Scientific의 SDHB 단클론 항체(CL0346)는 인간 SDHB 단백질을 인식하며 Western blot 및 IHC(P) 적용에 적합합니다. 고순도 Protein A 정제 항체로, 액상 형태이며 장기 보관 시 -20°C에서 안정적입니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL0346 |
| Immunogen | Recombinant protein corresponding to Human SDHB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2786986 |
Product Specific Information
Immunogen sequence:
EGKQQYLQSI EEREKLDGLY ECILCACCST SCPSYWWNGD KYLGPAVLMQ AYRWMIDSRD DFTEERLAKL QDPFSLYRCH TIMNCTRTCP KGLNPGKAIA EIKKMMATY
Target Information
Complex II of the respiratory chain is involved in the oxidation of succinate and transfers electrons from FADH to CoQ. This complex consists of four nuclear-encoded subunits located in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters that may form the enzyme's iron-sulfur centers. Mutations in this gene are associated with paragangliomas and pheochromocytoma, linking mitochondrial dysfunction to tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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