Thermo Fisher Scientific GATA-3 (Breast and Urothelial Marker) Recombinant Rabbit Monoclonal Antibody (GATA3/7686R)
GATA-3 단백질을 표적하는 재조합 토끼 단클론 항체로, 유방암 및 요로상피암 조직의 면역조직화학(IHC) 분석에 최적화됨. 인간 시료 반응성, HEK293 발현 시스템, 고순도 Protein A/G 정제, 액상 형태로 4°C 보관.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific GATA-3 (Breast and Urothelial Marker) Recombinant Rabbit Monoclonal Antibody (GATA3/7686R)
Thermo Fisher Scientific GATA-3 (Breast and Urothelial Marker) Recombinant Rabbit Monoclonal Antibody (GATA3/7686R)
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | GATA3/7686R |
| Immunogen | Recombinant fragment (around aa150–250) of human GATA-3 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Human breast or urothelial carcinoma tissue
- Cellular Location: Nucleus
Target Information
The genes for all four subunits of the T-cell antigen receptor (alpha, beta, gamma, and delta) are controlled by distinct enhancers and their enhancer-binding proteins. Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all four TCR genes.
GATA3 was shown to be an enhancer-binding protein containing a zinc finger domain and is abundantly expressed in the T-lymphocyte lineage, participating in T-cell receptor gene activation through enhancer binding.
Labastie et al. (1994) cloned the human gene consisting of six exons distributed over 17 kb of DNA. Its two zinc fingers are encoded by separate exons highly conserved with those of GATA1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.