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Thermo Fisher Scientific Phospho-ATR (Thr1989) Monoclonal Antibody (GT222)
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Phospho-ATR (Thr1989) 단백질을 특이적으로 인식하는 mouse monoclonal antibody. Western blot, ICC/IF, IP에 적합. DNA 손상 반응 연구 및 세포 주기 조절 기전 분석에 활용 가능. Protein A 정제, 1 mg/mL 농도, 보존 안정성 우수.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 03. 오전 12:45
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Thermo Fisher Scientific MA527731 Phospho-ATR (Thr1989) Monoclonal Antibody (GT222) 100 ul pk판매 단위 pk ·
재고 확인 필요
731,200원VAT 포함 804,320원
Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-ATR (Thr1989) Monoclonal Antibody (GT222)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| Immunoprecipitation (IP) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT222 |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ATR (phospho Thr1989). The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2735311 |
Product Specific Information
- Positive Control: HCT116, HCT116 (100 J/m² UVC and recover for 6 hr)
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
The ATR protein is a serine/threonine kinase and a DNA damage sensor that activates cell cycle checkpoint signaling upon DNA stress. It phosphorylates and activates several proteins involved in the inhibition of DNA replication and mitosis, promoting DNA repair, recombination, and apoptosis. It also plays a critical role in maintaining fragile site stability and centrosome duplication. Defects in this gene are associated with Seckel syndrome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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