Thermo Fisher Scientific ING3 Polyclonal Antibody
Human ING3 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 IHC에 사용 가능. N-terminal 합성 펩타이드(aa 36-85)를 면역원으로 제작. 액상 형태, 0.5 mg/mL 농도, PBS + 2% sucrose buffer에 보관. -20°C에서 저장, 연구용 전용.
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- PA540702
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Thermo Fisher Scientific ING3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.2–1 µg/mL | - |
| Immunohistochemistry (IHC) | – | 1 publication available |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human ING3 (aa 36–85) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2576933 |
Product Specific Information
- Peptide sequence: MDQLEQRVSE FFMNAKKNKP EWREEQMASI KKDYYKALED ADEKVQLANQ
- Sequence homology: Cow 100%, Dog 100%, Guinea Pig 100%, Horse 100%, Human 100%, Mouse 100%, Rabbit 100%, Rat 100%, Zebrafish 100%
Target Information
The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis.
It contains a PHD-finger motif commonly found in chromatin remodeling proteins.
This gene activates p53 trans-activated promoters, including p21/waf1 and bax.
Overexpression inhibits cell growth and induces apoptosis.
Allelic loss and reduced expression have been observed in head and neck cancers.
Two alternatively spliced transcript variants encoding different isoforms are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-40702_ING3_Q9NXR8-1_Rabbit.svg, PA5-40702_ING3_Q9NXR8-1_Rabbit_PDP.jpeg)
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