Thermo Fisher Scientific ERAS Polyclonal Antibody
Mouse ERAS 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot에 최적화되어 있습니다. 보존제가 없는 액상 형태이며, 고순도의 Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the center region of Mouse ERAS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788595 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Mouse ERAS.
Target Information
The human ERAS gene was initially reported as a processed pseudogene (HRasp, Ha-Ras2), with several base substitutions in coding regions, but was later described as potentially encoding a functional human ERAS protein.
The ERAS oncogene supports tumorigenic growth of embryonic stem cells by producing a constitutively active Ras protein. ERAS protein shares less than 50% amino acid identity with H-Ras, another Ras family member, but key domains essential for Ras function are highly conserved.
The protein contains amino-acid residues identical to those present in active mutants of Ras and causes oncogenic transformation in NIH 3T3 cells.
Human ERAS gene is localized in the chromosomal region Xp11.23.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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