Thermo Fisher Scientific CD8a Monoclonal Antibody (SK1), APC-eFluor 780, eBioscience
인간 CD8a 항원을 인식하는 SK1 단클론 항체로, APC-eFluor 780 형광체가 결합되어 있습니다. Flow cytometry 분석용으로 최적화되어 있으며, 고순도 친화 크로마토그래피 정제 제품입니다. 4°C 보관, 빛 차단 필요. 연구용으로만 사용됩니다.
- 카탈로그번호
- 47-0087-4x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD8a Monoclonal Antibody (SK1), APC-eFluor 780, eBioscience
Thermo Fisher Scientific CD8a Monoclonal Antibody (SK1), APC-eFluor 780, eBioscience
Applications and Tested Dilution
- Application: Flow Cytometry
- Tested Dilution: 5 µL (0.5 µg)/test
- Publications: View 15 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), APC-eFluor™ 780, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SK1 |
| Conjugate | APC-eFluor™ 780 |
| Excitation / Emission Max | 756 / 785 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2016617 |
Additional Formats Available
- Alexa Fluor 700
- APC
- Brilliant UV 805
- Brilliant Violet 650
- eFluor 450
- FITC
- NovaFluor Blue 610-70S
- NovaFluor Blue 660-120S
- NovaFluor Blue 690
- NovaFluor Yellow 730
- NovaFluor Yellow 755
- PE
- PE-Cyanine7
- PE-eFluor 610
- PerCP-eFluor 710
- Super Bright 436
- Super Bright 600
- Super Bright 702
- Request custom conjugation
Product Specific Information
The SK1 monoclonal antibody reacts with the human CD8a molecule (32–34 kDa), expressed as a heterodimer (CD8α/β) or homodimer (CD8α/α). CD8a is found on thymocytes, T cells, and NK cells, binding MHC class I and associating with tyrosine kinase p56lck to regulate T-cell development and activation.
- Applications Reported: Flow cytometric analysis
- Applications Tested: Pre-titrated and validated using normal human peripheral blood cells at 5 µL/test (0.5 µg)
- Cell range: 10⁵–10⁸ cells/test
- Excitation/Emission: 633–647 nm / 780 nm (Red laser)
- Light Sensitivity: Protect from light; tandem dye sensitive to photo-oxidation
- Fixation: Samples may be stored up to 3 days at 4°C in the dark using IC Fixation Buffer (Product #00-8222) or 1-step Fix/Lyse Solution (Product #00-5333)
- Filtration: 0.2 µm post-manufacturing filtered
Target Information
CD8 is a type I transmembrane glycoprotein involved in T cell differentiation and activation. It acts as a co-receptor with TCR for MHC-I molecules. CD8α chain binds MHC-I and is expressed on T cells, NK cells, monocytes, and dendritic cells. Interaction with MHC-I/peptide complexes triggers Lck recruitment, cytokine production, and cytotoxic T lymphocyte activation, essential for immune defense and tumor clearance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.