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Thermo Fisher Scientific DNMT3L Monoclonal Antibody (S117-9)
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DNMT3L 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, ICC, IP 등 다양한 응용에 사용 가능. 인간 DNMT3L(aa 1–387) 융합단백질을 면역원으로 제작. 1 mg/mL 액상 형태로 -20°C 보관. 연구용으로만 사용.
- 판매단위
- pk
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마지막 업데이트 2025. 07. 31. 오전 11:25
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Thermo Fisher Scientific MA527628 DNMT3L Monoclonal Antibody (S117-9) 100 ug pk판매 단위 pk ·
재고 확인 필요
821,100원VAT 포함 903,210원
Thermo Fisher Scientific · Thermo Fisher Scientific DNMT3L Monoclonal Antibody (S117-9)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | Assay-Dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S117-9 |
| Immunogen | Fusion protein amino acids 1–387 of human DNMT3L |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735170 |
Target Information
Methylation of DNA at cytosine residues in mammalian cells is a heritable, epigenetic modification essential for proper gene expression, genomic imprinting, and development. Three families of mammalian DNA methyltransferases have been identified: DNMT1, DNMT2, and DNMT3.
- DNMT1: Maintenance methyltransferase, active during DNA replication.
- DNMT3A and DNMT3B: De novo methyltransferases, highly expressed in embryonic stem cells.
- DNMT2: Low expression in adult tissues, minimal impact on DNA methylation.
- DNMT3L: Catalytically inactive regulatory factor for DNMT3A and DNMT3B, expressed in embryonic stem cells, testis, ovaries, and thymus. Forms heterotetrameric complexes with DNMT3A or DNMT3B and contains an N-terminal ADD domain and a C-terminal methyltransferase-like domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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