Thermo Fisher Scientific BNC1 Polyclonal Antibody
Human BNC1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 Immunohistochemistry에 적합. 고순도 Affinity chromatography 정제, PBS/glycerol buffer 포함. 세포 내 Basonuclin 발현 연구용으로 사용.
- 카탈로그번호
- PA5103313
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BNC1 (Accession Q01954), corresponding to amino acid residues S510–N560 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852658 |
Product Specific Information
Antibody detects endogenous levels of total Basonuclin.
Target Information
Bnc1 is a 994 amino acid transcription factor specific for squamous epithelium and keratinocytes at an early stage of terminal differentiation. It is a zinc finger protein with three separated pairs of zinc fingers and a nuclear localization signal. Bnc1 shuttles between the nucleus and cytoplasm depending on the proliferative potential of the cell. It is expressed in the basal cell layer of the epidermis, hair follicles, and abundantly in germ cells of testis and ovary, with lower expression in thymus, spleen, mammary glands, placenta, brain, and heart. It plays a regulatory role in keratinocyte proliferation and rRNA transcription, and contributes to the differentiation of spermatozoa and oocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: PA5-103313_BNC1_Q01954-1_Rabbit_PDP.jpeg)
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