Thermo Fisher Scientific IGFBP5 Polyclonal Antibody
IGFBP5 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 ELISA에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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- PA579453
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| ELISA | 0.1–0.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived human IGFBP5 recombinant protein (Position: A60–E272) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with 4 mg trehalose |
| Contains | 0.05 mg sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2746569 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
The insulin-like growth factor-binding proteins (IGFBPs) are a family of homologous proteins that co-evolved with the IGFs. They act as shuttle molecules for soluble IGFs and regulate IGF signaling. IGFBPs influence IGF bioavailability, concentration, and distribution in the extracellular environment, and may also have IGF-independent biological functions.
Seven IGFBPs have been identified, each differing in tissue distribution, half-life, and modulation of IGF interactions. IGFBP1 is negatively regulated by insulin and highly expressed during fetal liver development. IGFBP2 may function as a chaperone for IGFs and is expressed in fetal eye and brain. IGFBP3, the most abundant, complexes with ~80% of serum IGFs. IGFBP3 and IGFBP4 are released by dermal fibroblasts after incision injury. IGFBP5 is secreted by myoblasts and may play a key role in muscle differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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