Thermo Fisher Scientific IDH3G Polyclonal Antibody
IDH3G 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 다클론 항체입니다. Western blot과 IHC(P)에서 검증되었으며, 인간, 돼지, 쥐 시료에 반응합니다. 액상 형태로 제공되며, 안정적인 보관을 위해 -20°C에서 보관합니다.
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- PA5142772
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Pig, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-DHLKLHSYATSIRK (aa 337–350) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933418 |
Product Specific Information
- This antibody is expected to recognize both reported isoforms (NP_004126.1; NP_777358.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses: one utilizes NAD(+) as the electron acceptor and the other NADP(+).
Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases (mitochondrial matrix localized) and two NADP(+)-dependent isocitrate dehydrogenases (one mitochondrial, one cytosolic).
NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer composed of two alpha subunits, one beta subunit, and one gamma subunit.
The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase and is a candidate gene for periventricular heterotopia.
Several alternatively spliced transcript variants have been described, though only some full-length forms have been determined.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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