Thermo Fisher Scientific IDH3B Polyclonal Antibody
IDH3B 단백질을 인식하는 Thermo Fisher Scientific의 염소 폴리클로날 항체. 인간, 마우스, 돼지, 랫트에 반응하며 Western blot에 적합. 0.5 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Pig, Rat |
| Host/Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-HAASRSQAEDVRVE (aa 33–46) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933417 |
Product Specific Information
- This antibody is expected to recognize isoform a (NP_008830.2) and isoform b (NP_777280.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:1,000.
Target Information
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses: one utilizes NAD(+) and the other NADP(+) as electron acceptors.
Five isocitrate dehydrogenases have been reported:
- Three NAD(+)-dependent enzymes localized to the mitochondrial matrix
- Two NADP(+)-dependent enzymes (one mitochondrial, one cytosolic)
NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated, rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer composed of two alpha subunits, one beta subunit, and one gamma subunit.
The protein encoded by this gene is the beta subunit of one NAD(+)-dependent isocitrate dehydrogenase isozyme. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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