Thermo Fisher Scientific CYP24A1 Monoclonal Antibody (1F8)
CYP24A1 단백질을 인식하는 Mouse monoclonal antibody (Clone 1F8). Western blot과 ELISA에 적합하며, 인간 시료 반응성. PBS buffer에 보존, 무방부제. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1F8 |
| Immunogen | CYP24A1 (NP_000773, 415–514 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
LMLNTQVLGS SEDNFEDSSQ FRPERWLQEK EKINPFAHLP FGVGKRMCIG RRLAELQLHL ALCWIVRKYD IQATDNEPVE MLHSGTLVPS RELPIAFCQR
Target Information
The CYP24A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. These proteins are monooxygenases that catalyze reactions involved in drug metabolism and the synthesis of cholesterol, steroids, and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the active form of vitamin D3, by hydroxylation of the side chain. It plays a key role in regulating vitamin D3 levels, calcium homeostasis, and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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