Thermo Fisher Scientific LIN7C Polyclonal Antibody
LIN7C 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체. Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합. 고순도 Protein A 정제, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific LIN7C Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human LIN7C (aa 86–197) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Protein assembly at the post-synaptic density (PSD) of neuronal synapses is mediated in part by interactions with PDZ motifs. Mammalian LIN-7 (MALS) proteins are homologs of C. elegans LIN-7, essential for vulval development. MALS proteins, also known as Veli (Vertebrate Lin-7), are abundant in kidney, followed by brain, liver, thymus, and heart, but undetectable in spleen. In cultured cortical neurons, MALS proteins cluster with PSD-95 and NMDA-type glutamate receptors, playing roles in neurotransmitter receptor recruitment and synaptic protein assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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