Thermo Fisher Scientific ASAH1 Polyclonal Antibody
ASAH1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(paraffin)에서 사용 가능. 고순도 항원 친화 크로마토그래피로 정제. 인간 반응성, 농도 1.03 mg/mL, 장기 보관 시 -20°C 권장.
- 카탈로그번호
- PA534831
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ASAH1 Polyclonal Antibody
Thermo Fisher Scientific ASAH1 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:3,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 197–395 of ASAH1 (Uniprot ID: Q13510) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.03 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal, 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2552183 |
Product Specific Information
- Recommended positive controls: NT2D1, mouse heart, mouse muscle
- Predicted reactivity: Mouse (81%), Rat (84%), Chimpanzee (100%), Bovine (88%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
ASAH1 encodes a member of the acid ceramidase family of proteins. Alternative splicing produces multiple transcript variants, including a preproprotein processed into alpha and beta subunits that form a mature lysosomal enzyme. This enzyme catalyzes ceramide degradation into sphingosine and free fatty acid. ASAH1 is overexpressed in several human cancers and may play a role in cancer progression. Mutations are associated with Farber lipogranulomatosis and spinal muscular atrophy with progressive myoclonic epilepsy. Related pathways include Innate Immune System and Sphingolipid metabolism.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information: www.P65Warnings.ca.gov
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.