
Thermo Fisher Scientific RPSA Polyclonal Antibody
Thermo Fisher Scientific의 RPSA Polyclonal Antibody는 인간 및 생쥐 반응성을 가진 Rabbit IgG 항체입니다. Western blot과 IHC에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 사용되며 다양한 종에서 높은 예측 반응성을 보입니다.
- 카탈로그번호
- PA527281
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–294 of Human RPSA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2544757 |
Product Specific Information
- Recommended positive controls: HepG2, Jurkat, Mouse brain
- Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (93%), Xenopus laevis (95%), Dog (100%), Pig (100%), Chicken (98%), Sheep (99%), Rhesus Monkey (100%), Bovine (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Laminins are extracellular matrix glycoproteins, major noncollagenous constituents of basement membranes. They play roles in cell adhesion, differentiation, migration, signaling, neurite outgrowth, and metastasis. Laminin effects are mediated through integrin and non-integrin laminin-binding receptors.
The gene encodes a high-affinity, non-integrin laminin receptor 1, also known as 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP), or p40 ribosome-associated protein. Its sequence is highly conserved, indicating key biological functions.
Expression is elevated in colon carcinoma and lung cancer cells, correlating with invasive and metastatic phenotypes. Multiple pseudogene copies exist, likely from retropositional events. Two alternatively spliced variants encode the same protein.
⚠ WARNING
This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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