Thermo Fisher Scientific CD142 Polyclonal Antibody
Thermo Fisher Scientific CD142 Polyclonal Antibody는 인간 CD142(Tissue Factor)에 반응하는 Rabbit IgG 항체입니다. WB 및 IHC(P) 실험에 적합하며, 고순도 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
- Publications: 1 publication available
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 10–295 of Human Tissue Factor (CD142, UniProt ID: P13726-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2544754 |
Product Specific Information
- Recommended positive controls: A431, HeLa
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes coagulation factor III, a cell surface glycoprotein that enables cells to initiate the blood coagulation cascade. It functions as the high-affinity receptor for coagulation factor VII, forming a complex that catalyzes initiation of the coagulation protease cascade via limited proteolysis.
Unlike other cofactors, which circulate as inactive precursors, this factor is a potent initiator when expressed on cell surfaces. It has three distinct domains: extracellular, transmembrane, and cytoplasmic.
No congenital deficiency of this protein has been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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