Thermo Fisher Scientific Fra1 Polyclonal Antibody
Fra1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat에서 반응합니다. Western Blot 및 ELISA에 적합하며, 고순도 Affinity Chromatography로 정제되었습니다. 액상 형태로 −20°C 보관하며 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–100 of human FOSL1 (NP_005429.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.67 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914480 |
Product Specific Information
- Positive test controls: HeLa, C6
- Localization: Nucleus
Immunogen sequence:
MFRDFGEPGP SSGNGGGYGG PAQPPAAAQA AQQKFHLVPS INTMSGSQEL QWMVQPHFLG PSSYPRPLTY PQYSPPQPRP GVIRALGPPP GVRRRPCEQI
Target Information
The v-Fos oncogene was initially detected in two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. Members of the c-Fos gene family, including c-Fos, Fos B, Fra-1, and Fra-2, encode nuclear phosphoproteins that are rapidly and transiently induced by various agents and function as transcriptional regulators for several genes.
In contrast to c-Jun proteins, which form homo- and heterodimers that bind specific DNA response elements, c-Fos proteins are only active as heterodimers with members of the Jun gene family. Selected ATF/CREB family members can also form leucine zipper dimers with Fos and Jun, exhibiting differential specificity and affinity for AP-1 and CRE sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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