Thermo Fisher Scientific BAIAP2 Monoclonal Antibody (OTI1F4), TrueMAB

Applications

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The BAIAP2 gene encodes a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane-bound G-proteins to cytoplasmic effector proteins and functions as an insulin receptor tyrosine kinase substrate, suggesting a role for insulin in the central nervous system.
It associates with downstream effectors of Rho small G proteins, involved in stress fiber formation and cytokinesis. BAIAP2 contributes to lamellipodia and filopodia formation in motile cells and may influence neuronal growth-cone guidance.
Additionally, it interacts with the dentatorubral-pallidoluysian atrophy gene, associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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