Thermo Fisher Scientific KIR3DL1 Polyclonal Antibody
인간 KIR3DL1 단백질을 표적으로 하는 Thermo Fisher Scientific의 폴리클로날 항체입니다. Western blot 등에 사용 가능하며, Rabbit IgG로 제조되었습니다. 고순도 항원 친화 크로마토그래피 정제, 액상 형태로 제공되며 4°C 또는 -20°C에서 안정적으로 보관 가능합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:3,000
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 1–269 of Human KIR3DL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547295 |
Product Specific Information
- Recommended positive controls: 293T, A431, Jurkat, Raji
- Predicted reactivity: Human (98%), Chimpanzee (91%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
KIR3DL1 belongs to the Killer cell immunoglobulin-like receptor (KIR) family, which are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells.
KIR genes are polymorphic and clustered on chromosome 19q13.4 within the leukocyte receptor complex (LRC).
KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by the length of the cytoplasmic domain (L or S).
Proteins with long cytoplasmic domains transduce inhibitory signals via immune tyrosine-based inhibitory motifs (ITIM), while short domains associate with TYRO protein tyrosine kinase binding protein to transduce activating signals.
Ligands for several KIR proteins are subsets of HLA class I molecules, indicating their key role in immune regulation.
⚠ WARNING: This product can expose you to chemicals including mercury, known to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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