Thermo Fisher Scientific GSTA1 Polyclonal Antibody
Thermo Fisher Scientific의 GSTA1 Polyclonal Antibody는 인간 및 생쥐 시료에서 Western blot, IHC, ICC/IF 분석에 적합합니다. 항원 친화 크로마토그래피로 정제된 고품질 항체로, 해독 효소 GSTA1 단백질을 검출합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 1–177 of Human GSTA1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.86 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547285 |
Product Specific Information
- Recommended positive controls: HepG2, mouse liver
- Predicted reactivity: Pig (86%), Sheep (83%), Rhesus Monkey (93%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the glutathione S-transferase family of enzymes that catalyze the conjugation of glutathione to electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and oxidative stress products. This process is essential for detoxification and protection against reactive oxygen species and lipid peroxidation.
Polymorphisms in this gene affect drug metabolism capacity. The gene is located in a cluster of similar genes and pseudogenes on chromosome 6. Alternative splicing generates multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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