Thermo Fisher Scientific TLR9 Monoclonal Antibody (5G5), Biotin
TLR9 단백질을 인식하는 mouse IgG2a 단일클론 항체로, Biotin으로 표지되어 있음. Western blot 및 inhibition assay에 사용 가능. 인간, 마우스 및 개 TLR9에 반응. 단백질 G로 정제된 액상 제품으로 연구용에 적합.
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Thermo Fisher Scientific TLR9 Monoclonal Antibody (5G5), Biotin
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50 |
| Inhibition Assays (IA) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5G5 |
| Immunogen | Purified fusion protein of extracellular domain of human TLR9 (AA 1–815) and human IgG Fc |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_3093955 |
Additional Formats
Product Specific Information
The monoclonal antibody 5G5 reacts with RAW macrophages and TLR9-transfected HEK293 cells, and is cross-reactive with canine TLR9.
Target Information
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns expressed on infectious agents and mediate cytokine production necessary for effective immune responses.
This gene is preferentially expressed in immune cell–rich tissues such as spleen, lymph node, bone marrow, and peripheral blood leukocytes. Studies in mice and humans indicate that this receptor mediates cellular responses to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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