Thermo Fisher Scientific Glucagon Receptor Recombinant Mouse Monoclonal Antibody (hGR-2 F6)

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

10 µg/mL

-

Inhibition Assays (IA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

hGR-2 F6

Immunogen

Recombinant human glucagon receptor.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

0.02% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3074393

Product Specific Information

Specificity: The antibody binds to the human glucagon receptor.

Target Information

Glucagon receptors are G-protein coupled receptors for glucagon and play a central role in the regulation of blood glucose levels and glucose homeostatsis. It regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Glucagon receptors also play an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G-proteins) and modulates the activity of down-stream effectors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.