Thermo Fisher Scientific Glucagon Receptor Recombinant Mouse Monoclonal Antibody (hGR-2 F6)
인간 글루카곤 수용체를 특이적으로 인식하는 마우스 유래 재조합 단클론 항체. ICC/IF 및 억제 분석에 사용 가능. HEK293 세포에서 발현되며 Protein A로 정제됨. 연구용으로만 사용 가능.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 10 µg/mL
Inhibition Assays (IA)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | hGR-2 F6 |
| Immunogen | Recombinant human glucagon receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074393 |
Product Specific Information
Specificity: The antibody binds to the human glucagon receptor.
Target Information
Glucagon receptors are G-protein coupled receptors for glucagon and play a central role in the regulation of blood glucose levels and glucose homeostasis. They regulate the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Glucagon receptors also play an important role in mediating responses to fasting. Ligand binding causes a conformational change that triggers signaling via guanine nucleotide-binding proteins (G-proteins) and modulates the activity of downstream effectors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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