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Thermo Fisher Scientific CHK2 Polyclonal Antibody
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CHK2 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간·마우스·랫트 반응성. IHC(P) 등 다양한 연구용에 적합. 항원 친화 크로마토그래피로 정제되어 고순도(>95%) 확보. DNA 손상 체크포인트 및 암 관련 연구에 활용 가능.
- 카탈로그번호
- PA586222
- 판매단위
- pk
카탈로그
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마지막 업데이트 2025. 08. 04. 오전 01:34
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Thermo Fisher Scientific PA586222 CHK2 Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
851,500원VAT 포함 936,650원
Thermo Fisher Scientific · Thermo Fisher Scientific CHK2 Polyclonal Antibody
Thermo Fisher Scientific CHK2 Polyclonal Antibody
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) [IHC (P)]: 1:50–1:200
Species Reactivity
- Human
- Mouse
- Rat
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 351–400 of Human Chk2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS (pH 7.2) with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2803013 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
CHEK2 (CHK2) is a serine/threonine kinase involved in the DNA damage checkpoint pathway. Mutations in CHK2 are associated with various cancers. CHK2 phosphorylates cell cycle modulators including tumor suppressor proteins and BRCA1, aiding survival after DNA damage. It is considered a putative tumor suppressor, with mutations linked to Li-Fraumeni syndrome and predisposition to sarcomas, breast cancer, and brain tumors.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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