Thermo Fisher Scientific SOX4 Recombinant Rabbit Monoclonal Antibody (4A1E8)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2,000-1:20,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

4A1E8

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 350-450 of human SOX4. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SOX4,uniProtId:Q06945-1,ncbiNodeId:9606,antigenRange:350-450,antigenLength:474,antigenImageFileName:MA5-55338_SOX4_Q06945-1_Rabbit.svg,antigenImageFileNamePDP:MA5-55338_SOX4_Q06945-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.2 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Product Specific Information

Immunogen Sequence: AAGRSPADHR GYASLRAASP APSSAPSHAS SSASSHSSSS SSSGSSSSDD EFEDDLLDLN PSSNFESMSL GSFSSSSALD RDLDFNFEPG SGSHFEFPDY C

Target Information

SOX genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. SOX genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of SOX genes cluster at a minimum of 40 different loci that rapidly diverged in various animal lineages. At present 30 SOX genes have been identified, and members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.