Thermo Fisher Scientific CDCA7L Monoclonal Antibody (OTI6C6), TrueMAB
CDCA7L 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot과 IHC(P)에서 검증됨. 인간 유래 항원(aa 1–337)을 기반으로 제작되었으며, 무보존제 PBS 버퍼에 동결건조 형태로 제공. 연구용으로 MYC 관련 종양 연구 및 세포사멸 경로 분석에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6C6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–337 of human CDCA7L produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Cell division cycle-associated 7-like protein (CDCA7L, also known as RAM2) is a transcription factor involved in transcriptional regulation and apoptotic signaling pathways.
It acts as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to its promoter.
CDCA7L plays an oncogenic role in mediating the transforming effect of MYC in medulloblastoma cells.
It may function downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3, CCND1/cyclin D1, and E2F1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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