Thermo Fisher Scientific SAE2 Polyclonal Antibody
Thermo Fisher Scientific SAE2 Polyclonal Antibody는 인간 SUMO1 활성화 효소 서브유닛 2(UBA2)를 인식하는 토끼 유래 IgG 항체입니다. Western blot, IHC, IP 등 다양한 응용에 적합하며, 액상 형태로 제공되어 안정적인 4°C 보관이 가능합니다. 연구용으로만 사용됩니다.
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- A302925Ax (2개 옵션)
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Thermo Fisher Scientific SAE2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 525 and 575 of Human SUMO1 Activating Enzyme Subunit 2 (UBA2, UniProt ID: Q9UBT2-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
Target Information
UBA2 is involved in covalent attachment of one protein to another, a key posttranslational modification. Ubiquitin is the most familiar of these modifiers, but SUMO (Sentrin) proteins—SUMO-1, SUMO-2, and SUMO-3—play crucial roles in stabilizing target proteins and regulating sub-cellular localization.
SUMO conjugation requires the coordinated action of the E1-activating enzyme SAE1/SAE2, the E2-conjugating enzyme Ubc9, and an E3-like SUMO ligase.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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