Thermo Fisher Scientific PFKP Monoclonal Antibody (OTI1D6), TrueMAB
PFKP 단백질을 표적으로 하는 Thermo Fisher Scientific의 단클론 항체로, Western blot, IHC, ICC/IF, Flow cytometry에 사용 가능. 인간, 마우스, 랫트 반응성. 고순도 친화 크로마토그래피 정제. -20°C 보관, 연구용 전용.
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Thermo Fisher Scientific PFKP Monoclonal Antibody (OTI1D6), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D6 |
| Immunogen | Full length human recombinant protein of human PFKP produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the γ phosphate of ATP, onto an acceptor amino acid in a substrate protein. Through this mechanism, protein kinases mediate most signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement, cell movement, apoptosis, and differentiation.
With more than 500 gene products, the protein kinase family is one of the largest in eukaryotes. It has been classified into 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases, including:
- Cyclic nucleotide-regulated protein kinase (PKA & PKG)
- Diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC)
- RAC/Akt protein kinase family
- Kinases that phosphorylate G protein-coupled receptors (ARK)
- Kinases that phosphorylate ribosomal protein S6 (RSK)
Notes
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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