Thermo Fisher Scientific CD249 (BP-1) Monoclonal Antibody (6C3), APC, eBioscience

Thermo Fisher Scientific CD249 (BP-1) Monoclonal Antibody (6C3), APC, eBioscience

Applications

• Flow Cytometry (Flow)

Tested Dilution: 0.5 µg/test
Publications: View 3 publications

Product Specifications

Additional Formats

• Unconjugated
• Biotin
• FITC
• PE
• PerCP-eFluor 710
• Request custom conjugation

Product Specific Information

The 6C3 monoclonal antibody reacts with mouse BP-1, also known as Ly-51 and 6C3 antigen. BP-1 is a 140 kDa type II transmembrane protein present on the surface as a disulfide-linked homodimer. It functions as an enzyme with aminopeptidase A (APA) activity and is expressed by bone marrow stromal cells, thymic cortical epithelial cells, and pre-B cells at early stages of B cell development. BP-1 expression on pre-B cells can be upregulated by IL-7.

Applications Reported: Flow cytometric analysis
Applications Tested: Tested on mouse bone marrow cells at ≤0.5 µg/test.
A test is defined as the amount of antibody that stains a cell sample in a final volume of 100 µL. Cell number should be empirically determined (10⁵–10⁸ cells/test). Antibody titration is recommended for optimal performance.

Excitation: 633–647 nm
Emission: 660 nm
Laser: Red Laser

Target Information

CD249 (BP-1) is involved in the catabolic pathway of the renin-angiotensin system and likely regulates growth and differentiation of early B-lineage cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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