Thermo Fisher Scientific CD275 (B7-H2) Monoclonal Antibody (MIH12), APC, eBioscience
인간 B7-H2 (CD275, ICOS Ligand)을 인식하는 MIH12 단클론 항체로, APC 형광 표지되어 있습니다. Flow Cytometry에 최적화되어 있으며, 5 µL/test로 사용 가능합니다. PBS 완충액에 0.2% BSA 포함, 4°C 암소 보관 권장.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD275 (B7-H2) Monoclonal Antibody (MIH12), APC, eBioscience
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (Frozen) (IHC (F)) | - | View 1 publication |
| Flow Cytometry (Flow) | 5 µL (0.125 µg)/test | View 6 publications |
| Functional Assay (Functional) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), APC, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MIH12 |
| Conjugate | APC |
| Excitation/Emission Max | 651/660 nm |
| Form | Liquid |
| Concentration | 5 µL/test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2573240 |
Available Formats
Product Specific Information
Description:
The MIH12 monoclonal antibody reacts with human B7RP-1, also known as B7h, B7-H2, GL50, and ICOS Ligand. B7RP-1, a member of the B7 family, has a predicted molecular weight of approximately 40 kDa and belongs to the Ig superfamily. It is expressed by activated monocytes/macrophages and binds to the ICOS molecule expressed by activated T cells. The ICOS/B7RP-1 interaction is important in T-cell costimulation.
Applications Reported:
This MIH12 antibody has been reported for use in flow cytometric analysis.
Applications Tested:
Pre-titrated and tested by flow cytometric analysis of normal human peripheral blood monocyte-derived dendritic cells. Recommended use: 5 µL (0.125 µg) per test in a final volume of 100 µL. Suitable for 10⁵–10⁸ cells/test.
Fluorescence Characteristics:
- Excitation: 633–647 nm
- Emission: 660 nm
- Laser: Red Laser
Filtration:
0.2 µm post-manufacturing filtered.
Target Information
Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and peripheral tissue cells that binds to the inducible co-stimulator receptor (ICOS).
ICOS belongs to the CD28/CD152 receptor family regulating T-cell activation and function.
ICOSL is expressed on monocytes, dendritic cells, and B cells, and can be induced by inflammatory stimuli in peripheral tissue.
Binding to ICOSL delivers a co-stimulatory signal for T-cell proliferation and cytokine secretion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.