Thermo Fisher Scientific JNK1/JNK2/JNK3 Polyclonal Antibody
JNK1/JNK2/JNK3를 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA, IP 등 다양한 응용에 적합합니다. Human, Mouse, Rat 반응성을 가지며, 고순도 Affinity chromatography로 정제되어 안정적인 결과를 제공합니다. 연구용 전용 시약입니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
| ELISA | 1 µg/mL | - |
| Immunoprecipitation (IP) | 0.5–4 µg antibody for 400–600 µg extracts | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–370 of human JNK1/2/3 (NP_6206371) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.94 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901514 |
Product Specific Information
- Positive Samples: SH-SY5Y, Mouse brain, Rat brain
- Immunogen sequence:
MSRSKRDNNF YSVEIGDSTF TVLKRYQNLK PIGSGAQGIV CAAYDAILER NVAIKKLSRP FQNQTHAKRA YRELVLMKCV NHKNIIGLLN VFTPQKSLEE FQDVYIVMEL MDANLCQVIQ MELDHERMSY LLYQMLCGIK HLHSAGIIHR DLKPSNIVVK SDCTLKILDF GLARTAGTSF MMTPYVVTRY YRAPEVILGM GYKENVDLWS VGCIMGEMVC HKILFPGRDY IDQWNKVIEQ LGTPCPEFMK KLQPTVRTYV ENRPKYAGYS FEKLFPDVLF PADSEHNKLK ASQARDLLSK MLVIDASKRI SVDEALQHPY INVWYDPSEA EAPPPKIPDK QLDEREHTIE EWKELIYKEV MDLEERTKNG
Target Information
C-Jun N-terminal Kinase (JNK), also known as Mitogen-activated protein kinase (MAPK8), is part of the MAPK superfamily of stress-activated protein kinases. MAPKs are serine-threonine kinases activated by various extracellular stimuli and mediate signal transduction from the cell surface to the nucleus.
JNK regulates proliferation, differentiation, transcription, and development. It is activated by stress and inflammatory signals and expressed as ten different isoforms due to mRNA splicing, with JNK1 and JNK2 being predominant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-116884_JNK1JNK2JNK3_P45984-1_Rabbit.svg
- PA5-116884_JNK1JNK2JNK3_P45984-1_Rabbit_PDP.jpeg
- PA5-116884_JNK1JNK2JNK3_P53779-1_Rabbit.svg
- PA5-116884_JNK1JNK2JNK3_P53779-1_Rabbit_PDP.jpeg
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