Thermo Fisher Scientific eIF3B/EIF3S9 Polyclonal Antibody
Rabbit 폴리클로날 항체로 eIF3B/EIF3S9 단백질을 인식합니다. Western blot, IHC, IP 등 다양한 응용에 사용 가능합니다. 0.2 mg/mL 액상 형태로 제공되며 4°C에서 보관합니다. 단백질 번역 개시 복합체 연구에 적합합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution / Amount |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 100–150 of human eukaryotic translation initiation factor 3, subunit B (EIF3B/EIF3S9) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
Target Information
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, required for multiple steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi, and eIF-5 to form the 43S pre-initiation complex (43S PIC). It stimulates mRNA recruitment and scanning for AUG recognition, and is involved in ribosomal recycling and prevention of premature subunit joining. The complex selectively regulates translation of mRNAs associated with cell proliferation, differentiation, and apoptosis. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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