Thermo Fisher Scientific eIF3B/EIF3S9 Polyclonal Antibody
eIF3B/EIF3S9 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 Immunoprecipitation에 사용 가능. Human 및 Mouse 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. 단백질 번역 개시 복합체 연구에 적합.
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Applications
- Western Blot (WB): 1:2,000–1:10,000
- Immunoprecipitation (IP): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of human eukaryotic translation initiation factor 3, subunit B (EIF3B/EIF3S9) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates recruitment of initiation factors (eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi, and eIF-5) to form the 43S pre-initiation complex (43S PIC). It promotes mRNA recruitment and scanning for AUG recognition, and is involved in ribosomal recycling and prevention of premature subunit joining. The complex also regulates translation of specific mRNAs related to cell proliferation, differentiation, and apoptosis through RNA stem-loop binding mechanisms. [UniProt]
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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