Thermo Fisher Scientific CD204 Polyclonal Antibody
Human MSR1/CD204에 특이적인 Rabbit Polyclonal Antibody로, WB 및 ELISA에 적합. 보존제 무첨가 제품으로 고순도 Protein A 및 Antigen affinity chromatography로 정제됨. 연구용으로만 사용 가능하며 장기 보관 시 -20°C 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human MSR1/CD204 protein (Lys77–Leu451) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C (short term). For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788101 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human MSR1/CD204.
Target Information
CD204 gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing. These macrophage-specific trimeric integral membrane glycoproteins are implicated in physiological and pathological processes such as atherosclerosis, Alzheimer’s disease, and host defense.
Type 1 and 2 isoforms mediate endocytosis of modified LDLs, while type 3 does not internalize modified LDL and remains trapped in the endoplasmic reticulum, exerting a dominant negative effect on the functional isoforms.
Diseases associated with MSR1 include Barrett Esophagus and Prostate Cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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