Thermo Fisher Scientific CD142 Monoclonal Antibody (TF9-10H10)
인간 및 비인간 영장류 반응성의 CD142(Tissue Factor) 단클론 항체로, 다양한 응용(서던 블롯, IHC, ICC, Flow Cytometry)에 사용 가능. 단백질 G로 정제된 액상형 제품이며, 1 mg/mL 농도로 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Immunohistochemistry (IHC) | - | View 2 publications |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
| Flow Cytometry (Flow) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Published Species | Cynomolgus monkey, Rhesus monkey |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TF9-10H10 |
| Immunogen | Denatured tissue factor isolated from human brain by the Factor VII affinity method |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.1M mannitol |
| Contains | <0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2101347 |
Product Specific Information
- This antibody does not react with rabbit.
- Mouse anti-Human CD142 antibody, clone TF9-10H10 recognizes human CD142 (Tissue Factor), the membrane receptor for coagulation factors VII and VIIa.
- It acts as the cell surface initiator of the coagulation cascade.
Target Information
This gene encodes coagulation factor III, a cell surface glycoprotein that enables cells to initiate blood coagulation cascades. It functions as the high-affinity receptor for coagulation factor VII, forming a complex that catalyzes the initiation of protease cascades through limited proteolysis.
Unlike other cofactors that circulate as inactive precursors, this factor is fully functional when expressed on cell surfaces. It contains three domains: extracellular, transmembrane, and cytoplasmic.
No congenital deficiency of this protein has been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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