Thermo Fisher Scientific Calbindin 1 (CALB1) Monoclonal Antibody (CALB1, 2782)
인간 Calbindin 1(CALB1)을 인식하는 mouse monoclonal antibody로, IHC(P) 및 peptide array에 적합합니다. 단백질 A/G로 정제된 액상 형태이며, 4°C에서 보관합니다. 신경계 및 칼슘 운반 관련 연구에 유용합니다.
- 카탈로그번호
- 793-MSM2-P1
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Calbindin 1 (CALB1) Monoclonal Antibody (CALB1, 2782)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CALB1, 2782 |
| Immunogen | Recombinant fragment (around aa 7–96) of human CALB1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Calbindin-D-28K (also termed vitamin D-dependent calcium-binding protein or cholecalcin) is a highly conserved 28 kDa calcium-binding protein with broad tissue distribution.
It belongs to the family of low molecular weight calcium-binding proteins (CaBPs), including calmodulin, S-100, parvalbumin, and troponin C. These proteins share homologous EF-hand type polypeptide folds for Ca²⁺ binding.
Calbindin-D-28K is found predominantly in subpopulations of central and peripheral nervous system neurons and in epithelial cells involved in Ca²⁺ transport, such as distal tubular cells and cortical collecting tubules of the kidney, and in enteric neuroendocrine cells.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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