Thermo Fisher Scientific MYOZ1 Polyclonal Antibody
Human MYOZ1 단백질에 특이적인 Rabbit Polyclonal Antibody. IHC(P)에서 1:50–1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 항체. 근절 조립 관련 단백질 연구에 적합. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MYOZ1. Recombinant protein control fragment (Product #RP-102832). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2644395 |
Product Specific Information
Immunogen sequence:
AELPKYKSFN RTAMPYGGYE KASKRMTFQM PKFDLGPLLS EPLVLYNQNL SNRPSFNRTP IPWLSSGEPV DYNVDIG
Antigen sequence identity:
- Mouse: 97%
- Rat: 97%
Target Information
Sarcomere assembly is regulated by the muscle protein titin, a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold for myofibrils and other muscle-related proteins.
The MYOZ1 gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1–Z2 domains and acts as a substrate of titin kinase—interactions critical for sarcomere assembly.
Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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