Thermo Fisher Scientific CD8 Monoclonal Antibody (3B5), Qdot 705
인간 CD8 항원을 인식하는 마우스 단클론 항체로 Qdot 705 형광체로 결합된 제품입니다. Flow Cytometry 등 다양한 형광 분석에 적합하며 고순도 정제 상태로 제공됩니다. 4°C 암소 보관, 연구용 전용.
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Thermo Fisher Scientific CD8 Monoclonal Antibody (3B5), Qdot 705
Applications
- Flow Cytometry (Flow)
Tested Dilution: Assay-dependent
Publications: View 12 publications
Miscellaneous PubMed
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Non-human primate, Rhesus monkey |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3B5 |
| Immunogen | Recognizes the CD8 antigen |
| Conjugate | Qdot™ 705 |
| Excitation / Emission Max | 300 / 702 nm |
| Form | Liquid |
| Purification | Purified |
| Storage Buffer | 0.05M borate, pH 8.3, with 1M betaine |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11180330 |
Additional Formats Available
- Unconjugated
- Alexa Fluor 405
- Alexa Fluor 647
- Alexa Fluor 700
- APC
- APC-Alexa Fluor 750
- FITC
- Pacific Blue
- Pacific Orange
- PE
- PE-Alexa Fluor 610
- PE-Cyanine5.5
- PE-Cyanine7
- PE-Texas Red
- PerCP
- Qdot 605
- Qdot 655
- Qdot 800
- TRI-COLOR
- Request custom conjugation
Target Information
Cluster of differentiation 8 (CD8) is a type I transmembrane glycoprotein of the immunoglobulin receptor family. It plays an integral role in signal transduction, T cell differentiation, and activation. CD8 is mainly expressed on T cells as a heterodimer of CD8α and CD8β, functioning as a co-receptor with the T cell receptor (TCR) for MHC class I molecules. It is also found on subsets of T cells, NK cells, monocytes, and dendritic cells as CD8α homodimers. Binding of MHC-I/peptide complexes triggers recruitment of Lck kinase, leading to lymphokine production, motility, and cytotoxic T lymphocyte (CTL) activation. Activated CTLs are critical for pathogen and tumor clearance. Differentiation of naïve CD8+ T cells into CTLs is enhanced by IL-2, IL-12, and TGF-β1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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