Thermo Fisher Scientific RAB3GAP1 Polyclonal Antibody
RAB3GAP1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 적합하며 인간 시료에 반응. 항원 친화 크로마토그래피로 정제된 액상 제품으로, 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human RAB3GAP1. The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.51 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2736492 |
Product Specific Information
- Positive Control: 293T, A431, HeLa, HepG2
- Predicted Reactivity: Mouse (96%), Zebrafish (81%), Xenopus laevis (91%), Bovine (96%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
RAB3GAP1 is a 981-amino acid protein belonging to the Rab3-GAP catalytic subunit family. Rab3 GAP p130 converts active RAB3-GTP to the inactive RAB3-GDP form and is required for normal eye and brain development. Defects in Rab3 GAP p130 cause Warburg micro syndrome 1 (WARBM1), a severe autosomal recessive disorder characterized by developmental abnormalities of the eye and central nervous system and by microgenitalia. The Rab3 GAP p130 protein may participate in neurodevelopmental processes such as proliferation, migration, and differentiation before synapse formation, as well as non-synaptic vesicular release of neurotransmitters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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