Thermo Fisher Scientific GRSF1 Recombinant Rabbit Monoclonal Antibody (11H24L16)

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

1:100

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

Expi293

Class

Recombinant Monoclonal

Type

Antibody

Clone

11H24L16

Immunogen

Protein corresponding to human GRSF1 [aa142-aa245] if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GRSF1,uniProtId:Q12849-1,ncbiNodeId:9606,antigenRange:142-245,antigenLength:480,antigenImageFileName:703456_GRSF1_Q12849-1_Rabbit.svg,antigenImageFileNamePDP:703456_GRSF1_Q12849-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2762392

Product Specific Information

This antibody is predicted to react with Monkey, Bovine, Pig, Mouse.

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Target Information

G-rich sequence factor 1 (GRSF1) is a regulator of post-transcriptional mitochondrial gene expression. It required for assembly of the mitochondrial ribosome and for recruitment of mRNS and IncRNA. GRSF1 binds RNAs containing the 14 base G-rich element. It preferentially binds RNAs transcribed from three contiguous genes on the light strand of mtDNA, the ND6 mRNA, and the long non-coding RNAs for MT-CYB and MT-NDS - each of which contains multiple consensus binding sequences.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.