Thermo Fisher Scientific Urokinase Monoclonal Antibody (05)
인간 Urokinase/PLAU를 인식하는 Mouse monoclonal 항체로, ELISA에 적합합니다. 보존제가 포함되지 않은 액상 형태이며 Protein A로 정제되었습니다. 단기 보관은 4°C, 장기 보관은 -20°C에서 권장됩니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
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Applications
- ELISA (ELISA)
Tested Dilution: 1:1,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 05 |
| Immunogen | Recombinant Human Urokinase/PLAU Protein (Met1–Leu431) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786756 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human Urokinase/PLAU.
Target Information
The gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer’s disease and decreased affinity for fibrin-binding.
This protein converts plasminogen to plasmin by cleavage of an Arg-Val bond. Plasmin cleaves this protein at a Lys-Ile bond to form a two-chain derivative (HMW-uPA), connected by a disulfide bond between the A-chain and catalytically active B-chain. HMW-uPA can be further processed into LMW-uPA by cleavage of chain A. LMW-uPA is active but does not bind to the uPA receptor.
Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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