Thermo Fisher Scientific BCAS4 Polyclonal Antibody
BCAS4 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot 및 IHC에 사용 가능하며, Human과 Mouse 시료에 반응. 항원 친화 크로마토그래피로 정제된 액상 항체로 안정적인 보관 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 14 amino acid peptide near the amino terminus of human BCAS4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154541 |
Product Specific Information
- Suggested positive control: NIH-3T3 cell lysate
- PA5-20907 can be used with blocking peptide PEP-1021.
Target Information
The Breast carcinoma amplified sequence (BCAS4) gene is localized to 20q13, a region often amplified in breast cancers. It was identified through cloning of a highly overexpressed 1.3 kb transcript resulting from the fusion of the last two exons of the BCAS3 and BCAS4 genes. This BCAS3–BCAS4 fusion transcript appears exclusively in the MCF7 cell line, but BCAS4 is also overexpressed in nine of thirteen breast cancer cell lines. Although the precise role of BCAS4 remains unclear, its mRNA is highly expressed in thymus, spleen, kidney, brain, and placenta, suggesting potential roles in multiple tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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