
Thermo Fisher Scientific Ribophorin I Polyclonal Antibody
Rabbit polyclonal antibody against human Ribophorin I (RPN1). Validated for IHC (Paraffin) and ICC/IF. Antigen affinity purified, supplied in PBS with 40% glycerol. Suitable for ER-associated protein studies.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RPN1. Recombinant protein control fragment (Product # RP-102438) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790093 |
Product Specific Information
Immunogen sequence:
KVHYENNSPF LTITSMTRVI EVSHWGNIAV EENVDLKHTG AVLKGPFSRY DYQRQPDSGI SSIRSFKTIL PAAAQDVYYR DEIGNVSTSH LLILDDSVEM EIRPRFPLFG GWKTHYIVGY NLPSYEYLYN LGDQYALKMR FV
Target Information
Ribophorins 1 and 2 are abundant and highly conserved glycoproteins residing in the endoplasmic reticulum that participate in ribosome binding. Mammalian oligosaccharyltransferase activity is associated with a protein complex composed of RPN1, RPN2, and an oligosaccharyltransferase protein.
RPN1 is a component of the proteasome base. The ubiquitin-like (UBL) domain of recombinant Rad23 interacts with proteasomes through the leucine-rich repeat domain of RPN1.
The RPN1 gene maps to chromosome 3 in somatic cell hybrids, and the RPN2 gene maps to chromosome 20 by in situ hybridization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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