Thermo Fisher Scientific BEND3 Polyclonal Antibody
BEND3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. IHC, ICC/IF, ELISA 등 다양한 응용 가능. 고순도 Protein A 정제, 안정적인 액상 형태로 제공. 연구용으로만 사용.
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Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human BEND3, amino acids 501–600 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Transcriptional repressor which associates with the NoRC (nucleolar remodeling complex) and plays a key role in repressing rDNA transcription. The sumoylated form modulates the stability of the NoRC complex component BAZ2A/TIP5 by controlling its USP21-mediated deubiquitination (PubMed:21914818, PubMed:26100909).
Binds to unmethylated major satellite DNA and is involved in the recruitment of the Polycomb repressive complex 2 (PRC2) to major satellites.
Stimulates the ERCC6L translocase and ATPase activities (PubMed:28977671). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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